Which of the following indicates the need for a daily controller medication?

A daily controller medication is typically required for individuals with severe persistent asthma due to the consistent and significant nature of their symptoms. Severe persistent asthma is characterized by frequent asthma attacks, nighttime symptoms occurring more than once a week, and limitations on physical activity. These patients experience daily symptoms that can significantly impact their quality of life and may not be controlled adequately with only a rescue inhaler, which is generally used for quick relief during symptoms or attacks.

In contrast, intermittent asthma is defined by symptoms occurring less than twice a week, requiring no daily medication, and often can be managed with as-needed rescue inhalers. Mild persistent asthma may require daily treatment in some cases, but it is less severe than severe persistent asthma and can often be controlled with lower doses of medication. Lastly, having no asthma symptoms does not warrant the use of controller medications since the condition is well managed without them. Thus, those with severe persistent asthma are the patient group most in need of a daily controller to manage their chronic condition effectively.